What You Should Know About GLP-1’s

Written By Anna Salerno

GLP-1 is a hormone produced in the intestines that plays a crucial role in regulating blood sugar levels and appetite. This hormone also delays the time it takes for the stomach to empty after eating, increasing feelings of satiation and fullness. Clinical studies have shown that the class of medication called GLP-1 receptor agonists can significantly reduce A1C levels in people with type 2 diabetes, helping to better manage diabetes and reduce the risk of complications associated with high blood sugar. There are several GLP-1 receptor agonists available on the market. Some of the commonly known ones include Trulicity, Victoza, Ozempic, Mounjaro, and Rybelsus. These medications may come in different formulations and have varying dosing schedules, as well as cost. 

 

GLP-1 drugs were originally prescribed to treat diabetes. However, they’ve gained recent popularity for their ability to help individuals lose weight. Due to the chronic nature of obesity, these drugs may need to be taken indefinitely to see lasting effects. It’s also important to note that these drugs are meant to be used in addition to healthy lifestyle changes and not as a replacement. Using GLP-1 drugs to manage weight loss is expensive, costing more than $1,000 per person each month. Since these drugs were not originally designed to treat weight loss, they may not be effective over the long term if used for a short period.  
 
Like any other drug, there is a risk of side effects with this medication class. Some of the more common side effects include: 

  • Nausea 

  • Vomiting 

  • Diarrhea 

  • Hypoglycemia 

  • Injection site reactions 

  • Decreased Appetite 

  • Constipation

It's important to note that some studies have suggested a link between GLP-1 and gastrointestinal adverse events (gastroparesis, pancreatitis, bowel obstruction) and thyroid tumors. It is essential to discuss any concerns or potential side effects with your healthcare provider before starting any new treatment. 

The information provided is for educational purposes and should not be used during any medical emergency or for the diagnosis or treatment of any conditions. Consult with your medical provider for diagnosis and treatment of all medical conditions. Call 911 for medical emergencies. 

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Anna Salerno
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